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Xenical
orlistat (OR lih stat)
What is the most important information I should know about Xenical?
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Xenical may decrease your body's absorption of some fat-soluble vitamins.
To ensure adequate nutrition, your doctor may recommend
taking a multivitamin that contains vitamins D, E, K, and beta-carotene.
Take your vitamin supplement once a day, at least 2 hours before or
after a dose of Xenical. |
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Do not take more of this medication than has been prescribed for you.
Doses greater than 120 mg three times a day have not been shown to
provide any additional weight-loss benefit. |
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Xenical blocks some of the fat that you eat from being absorbed
by your body. |
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Xenical is used in the management of obesity including weight loss
and weight maintenance when used with a reduced-calorie diet. |
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Xenical may also be used for purposes other than those listed in this
medication guide. |
What should I discuss with my healthcare provider before
taking Xenical?
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Do not take Xenical without first talking to your doctor if you have |
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a chronic malabsorption syndrome, or |
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You may not be able to take Xenical if you have any of the conditions
listed above. |
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Before taking Xenical, talk to your doctor if you |
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have a history of kidney stones, |
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have anorexia or bulimia, |
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take any other weight-loss medicine, or |
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take cyclosporine (Sandimmune, Neoral). |
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You may not be able to take Xenical, or you may require a dosage
adjustment or special monitoring during your treatment if you have any
of the conditions listed above. |
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Xenical is in the FDA pregnancy category B. This means that it is not
expected to harm an unborn baby. Do not take Xenical without first
talking to your doctor if you are pregnant. |
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It is not known whether Xenical passes into breast milk. Do not take
Xenical without first talking to your doctor if you are breast-feeding a
baby. |
How should I take Xenical?
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Take Xenical exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to
explain them to you. |
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Take each dose with a full glass of water. |
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Xenical is usually taken with each main meal that contains fat.
Xenical can be taken during meals or up to one hour after a meal. |
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Each time you take Xenical, your meal should contain no more than
about 30% of calories from fat. Evenly divide your daily intake of fat,
carbohydrates, and protein over three main meals a day. Talk to your
doctor about following a healthy eating plan. |
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If you miss a meal, or if you have a meal without fat, you can skip
your dose of Xenical for that meal also. |
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If Xenical is taken with any one meal that is very high in fat, there
is an increased chance of digestive side effects. |
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Do not take more of this medication than has been prescribed for you.
Doses greater than 120 mg three times a day have not been shown to
provide an additional weight-loss benefit. |
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• |
Xenical may decrease your body's absorption of some fat-soluble
vitamins. To ensure adequate nutrition, your doctor may recommend taking
a multivitamin that contains vitamins D, E, K, and beta-carotene. Take
your vitamin supplement once a day, at least 2 hours before or after a
dose of Xenical. |
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Store Xenical at room temperature away from moisture and heat. |
What happens if I miss a dose?
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Take the missed dose up to one hour after a meal. If more than one
hour has passed since your last meal, skip the dose you missed and take
only your next regularly scheduled dose as directed. Do not take a
double dose of this medication. |
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If you miss a meal, or if you have a meal without fat, you can skip
your dose of Xenical for that meal also. |
What happens if I overdose?
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Seek emergency medical attention. |
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Symptoms of an Xenical overdose are not known. |
What should I avoid while taking Xenical?
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Xenical may decrease your body's absorption of some fat-soluble
vitamins. To ensure adequate nutrition, your doctor may recommend taking
a multivitamin that contains vitamins D, E, K, and beta-carotene. Take
your vitamin supplement once a day, at least 2 hours before or after a
dose of Xenical. |
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Each time you take Xenical, your meal should contain no more than
about 30% of calories from fat. Evenly divide your daily intake of fat,
carbohydrates, and protein over three main meals a day. Talk to your
doctor about following a healthy eating plan. |
What are the possible side effects of Xenical?
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Stop taking Xenical and seek emergency medical attention if you
experience a rare allergic reaction including shortness of breath;
closing of your throat; swelling of your lips, tongue, or face; or hives. |
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Other, less serious side effects are more likely to occur. Continue to
take Xenical and talk to your doctor if you experience |
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an urgent need to go to the bathroom, |
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an increased number of bowel movements, |
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an inability to control bowel movements, or |
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orange or brown colored oil in your stool. |
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The bowel changes listed above are a natural effect of blocking fat
and indicate that Xenical is working. They generally occur early in
treatment, particularly after meals containing higher amounts of fat
than are recommended. These symptoms are usually temporary and lessen or
disappear as you continue treatment and keep to your recommended diet of
meals containing 30% fat. |
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Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
bothersome. |
What other drugs will affect Xenical?
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Do not take Xenical without first talking to your doctor if you are
taking any of the following medicines: |
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cyclosporine (Neoral, Sandimmune), or |
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You may not be able to take Xenical, or you may require a dosage
adjustment or special monitoring during your treatment if you are taking
any of the medicines listed above. |
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Before taking Xenical, tell your doctor if you are taking any of the
following medicines to lower cholesterol: |
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atorvastatin (Lipitor), |
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pravastatin (Pravachol), or |
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You may require a dosage adjustment or special monitoring during
treatment if you are taking any of the cholesterol-lowering medicines
listed above. |
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Xenical may decrease your body's absorption of some fat-soluble
vitamins. To ensure adequate nutrition, your doctor may recommend taking
a multivitamin that contains vitamins D, E, K, and beta-carotene. Take
your vitamin supplement once a day, at least 2 hours before or after a
dose of Xenical. |
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Drugs other than those listed here may also interact with Xenical.
Talk to your doctor and pharmacist before taking or using any other
prescription or over-the-counter medicines. |
Where can I get more information?
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Your pharmacist has more information about Xenical written for health
professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
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