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Wellbutrin
bupropion (byoo PROE pee on)
Wellbutrin, Wellbutrin SR, Zyban SR
What is the most important information I should know about Wellbutrin?
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Do not stop taking Wellbutrin without first talking to your doctor.
It may be several weeks before you begin to feel better, and you may
require continuous treatment for quite some time. |
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Avoid alcohol or drink it only in moderation while taking Wellbutrin.
Alcohol may increase the risk of having a seizure while taking
Wellbutrin. However, if you drink a lot of alcohol and suddenly stop,
you may also increase the risk of having a seizure. Therefore, talk to
your doctor about alcohol use before starting treatment with Wellbutrin. |
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Do not crush, chew, or break the sustained-release tablets (Wellbutrin
SR and Zyban). Swallow them whole. They are specially formulated to
release slowly in your body. If you are unsure whether you have a
sustained-release formulation, ask your pharmacist, doctor, or nurse. |
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Wellbutrin may be used to treat different medical conditions. You
should not be taking more than one product containing bupropion
at a time (e.g., Wellbutrin and Zyban). Talk to your doctor if a second
product containing bupropion is prescribed for you. Too much of this
medicine can increase the risk of a seizure. |
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Wellbutrin is an antidepressant medication. The exact way that
Wellbutrin works is unknown. |
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Wellbutrin is used to relieve symptoms of depression such as
feelings of sadness, worthlessness or guilt, loss of interest in daily
activities, changes in appetite, tiredness, sleeping too much, insomnia,
and thoughts of death or suicide. Bupropion is also used to help people stop
smoking by reducing withdrawal effects. |
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Wellbutrin may also be used for purposes other than those listed in
this medication guide. |
What should I discuss with my healthcare provider before
taking Wellbutrin?
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Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor
(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or
tranylcypromine (Parnate) in the last 14 days. |
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Do not take Wellbutrin if you have epilepsy or another type of seizure
disorder, or if you have ever been diagnosed with anorexia or bulimia.
Wellbutrin may increase the risk of having a seizure if you have any of
these conditions. |
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Before taking this medication, tell your doctor if you have any other
medical conditions such as heart, liver, or kidney disease. You may
require a dosage adjustment or special monitoring during your treatment
with Wellbutrin. |
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Wellbutrin may be used to treat different medical conditions. You
should not be taking more than one product containing bupropion at a
time (e.g., Wellbutrin and Zyban). Talk to your doctor if a second
product containing bupropion is prescribed for you. Too much of this
medicine can increase the risk of a seizure. |
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Wellbutrin is in the FDA pregnancy category B. This means that it is
unlikely to harm an unborn baby. Do not take Wellbutrin without first
talking to your doctor if you are pregnant. |
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It is not known whether Wellbutrin will harm a nursing baby. Do not
take Wellbutrin without first talking to your doctor if you are
breast-feeding a baby. |
How should I take Wellbutrin?
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Take Wellbutrin exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to
explain them to you. |
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Take each dose with a full glass of water. |
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Do not crush, chew, or break the sustained-release tablets (Wellbutrin
SR and Zyban). Swallow them whole. They are specially formulated to
release slowly in your body. If you are unsure whether you have a
sustained-release formulation, ask your pharmacist, doctor, or nurse. |
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Never take more Wellbutrin in one dose or in one day than is directed
by your doctor. Taking too much Wellbutrin can increase the risk of a
seizure. Maximum doses of Wellbutrin are as follows: |
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No single dose of the regular-release product Wellbutrin should be
more than 150 mg, and doses should be taken at least 6 hours apart with
a maximum daily dose of 450 mg. |
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Single doses of the sustained-release product Wellbutrin SR should not
exceed 200 mg and should be taken at least 8 hours apart with a maximum
daily dose of 400 mg. |
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Single doses of Zyban should not exceed 150 mg and doses should be
taken at least 8 hours apart with a maximum daily dose of 300 mg. |
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Take Wellbutrin exactly as directed by your doctor. |
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If you are taking Zyban to help you stop smoking, a target "quit
date" is usually set for a date during the second week of treatment
with Zyban. Although it is not physically harmful to smoke while taking
Zyban, continuing to smoke after the date you set to stop smoking will
seriously reduce your chance of breaking the smoking habit. Nicotine
replacement products (patches or gum) can be used during treatment with
Zyban under the supervision of a doctor. Zyban and a nicotine
replacement product together may raise your blood pressure and your
doctor will probably want to check your blood pressure regularly. Do
not smoke at any time if you are using a nicotine product along with
Zyban as this can cause serious side effects from too much nicotine. |
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Do not stop taking Wellbutrin without first talking to your doctor. It
may be several weeks before you begin to feel better, and you may
require continuous treatment for quite some time. |
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Wellbutrin SR and Zyban tablets may have an odor. If present, this
odor is normal. |
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Store Wellbutrin at room temperature away from moisture and heat. |
What happens if I miss a dose?
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Skip the missed dose and take only your next regularly scheduled dose.
Do not take a double dose. |
What happens if I overdose?
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Seek emergency medical attention. |
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Symptoms of a Wellbutrin overdose include seizures, hallucinations,
loss of consciousness, weakness, a fast heartbeat, and heart attack. |
What should I avoid while taking Wellbutrin?
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Avoid alcohol or drink it only in moderation while taking Wellbutrin.
Alcohol may increase the risk of having a seizure while taking
Wellbutrin. However, if you drink a lot of alcohol and suddenly stop,
you may also increase the risk of having a seizure. Therefore, talk to
your doctor about alcohol use before starting treatment with Wellbutrin. |
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Use caution when driving, operating machinery, or performing other
hazardous activities. Wellbutrin may cause dizziness or drowsiness. If
you experience dizziness or drowsiness, avoid these activities. |
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Dizziness may be more likely to occur when you rise from a sitting or
lying position. Rise slowly to prevent dizziness and a possible fall. |
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Bupropion may be used to treat different medical conditions. You
should not be taking more than one product containing bupropion at a
time (e.g., Wellbutrin and Zyban). Talk to your doctor if a second
product containing bupropion is prescribed for you. Too much of this
medicine can increase the risk of a seizure. |
What are the possible side effects of Wellbutrin?
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If you experience any of the following uncommon but serious side
effects, stop taking Wellbutrin and seek emergency medical attention or
contact your doctor immediately: |
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an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives); |
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fast or irregular heartbeats. |
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Other, less serious side effects may be more likely to occur. Continue
to take Wellbutrin and talk to your doctor if you experience |
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tremors, restlessness, agitation, or anxiety; |
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dizziness or drowsiness; |
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flulike symptoms such as aching muscles, fatigue, and discomfort; |
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Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
bothersome. |
What other drugs will affect Wellbutrin?
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Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor
(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or
tranylcypromine (Parnate) in the last 14 days. |
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Many drugs can interact with Wellbutrin, resulting in side effects and/or
decreased effectiveness of the medication. Do not take any other
prescription or over-the-counter medicines, including herbal or natural
products, without first talking to your doctor during treatment with
Wellbutrin. |
Where can I get more information?
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Your pharmacist has more information about Wellbutrin written for
health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed |
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Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist.
Click here for more information on Wellbutrin
from the manufacturer.
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