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Generic Name: hydrocodone and phenylephrine (high
droe KOE dohn and fen ill EH frin)
Brand Names:
Lortuss HC, Nalex-DH
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What is the most important information I should know
about hydrocodone and phenylephrine?
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Use caution when driving, operating machinery, or
performing other hazardous activities. Hydrocodone and
phenylephrine may cause dizziness or drowsiness. If you
experience dizziness or drowsiness, avoid these activities. |
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• |
Use alcohol cautiously. Alcohol may increase drowsiness
and dizziness while taking hydrocodone and phenylephrine. |
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Hydrocodone and phenylephrine may increase the effects
of other drugs that cause drowsiness, including
antidepressants, alcohol, antihistamines, sedatives (used
to treat insomnia), pain relievers, anxiety medicines,
seizure medicines, and muscle relaxants. Tell your doctor
about all medicines that you are taking, and do not take
any other medicine without first talking to your doctor. |
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Hydrocodone is habit forming. It is possible become
physically and/ or psychologically dependent on the
medication. Do not take more than the prescribed amount of
medication or take it for longer than is directed by your
doctor. Withdrawal effects may occur if hydrocodone and
phenylephrine is stopped suddenly after several weeks of
continuous use. Your doctor may recommend a gradual
reduction in dose. |
What is hydrocodone and phenylephrine?
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Hydrocodone is a narcotic. It is a pain reliever and a
cough suppressant. |
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Phenylephrine is a decongestant. It works by
constricting (shrinking) blood vessels (veins and arteries)
in the body. Constriction of blood vessels in the sinuses
and nose decreases congestion. |
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Hydrocodone and phenylephrine is used to treat cough and
nasal congestion associated with the common
cold, sinus infections, the flu, and bronchitis. |
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Hydrocodone and phenylephrine may also be used for
purposes other than those listed in this medication guide. |
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Do not take hydrocodone and phenylephrine if you have
taken a monoamine oxidase inhibitor (MAOI) such as
isocarboxazid (Marplan), phenelzine (Nardil),
tranylcypromine (Parnate), or selegiline (Eldepryl) in the
last 14 days. A dangerous drug interaction could occur,
leading to serious side effects. |
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Before taking hydrocodone and phenylephrine, tell your
doctor if you have |
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epilepsy or another seizure disorder; |
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been diagnosed with sleep
apnea (periods of not breathing during sleep); |
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bladder problems or difficulty urinating; |
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You may not be able to take hydrocodone and
phenylephrine, or you may require a dosage adjustment or
special monitoring during treatment if you have any of the
conditions listed above. |
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Hydrocodone and phenylephrine is in the FDA pregnancy
category C. This means that it is not known whether
hydrocodone and phenylephrine will be harmful to an unborn
baby. Do not take hydrocodone and phenylephrine without
first talking to your doctor if you are pregnant or could
become pregnant during treatment. |
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Hydrocodone and phenylephrine passes into breast
milk and may be harmful to a nursing baby. Do not
take hydrocodone and phenylephrine without first talking
to your doctor if you are breast-feeding a baby. |
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If you are over 65 years of age, you may be more likely
to experience side effects from hydrocodone and
phenylephrine. Your doctor may prescribe a lower dose of
this medication. |
How should I take hydrocodone and phenylephrine?
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Take hydrocodone and phenylephrine exactly as directed
by your doctor. If you do not understand the directions on
your prescription bottle, ask your pharmacist, nurse, or
doctor to explain the instructions to you. |
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Hydrocodone and phenylephrine can be taken with or
without food. |
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Take the oral tablets and capsules with a full glass of
water. |
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To ensure that you get a correct dose, measure the
liquid form of hydrocodone and phenylephrine with a
special dose-measuring spoon or cup, not with a regular
table spoon. If you do not have a dose-measuring device,
ask your pharmacist where you can get one. |
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Do not take more of this medication or take it for
longer than is recommended. If your symptoms do not
improve, or if they worsen, talk to your doctor. |
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Hydrocodone is habit forming. It is possible become
physically and/ or psychologically dependent on the
medication. Do not take more than the prescribed amount of
medication or take it for longer than is directed by your
doctor. Withdrawal effects may occur if hydrocodone and
phenylephrine is stopped suddenly after several weeks of
continuous use. Your doctor may recommend a gradual
reduction in dose. |
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Store hydrocodone and phenylephrine at room temperature
away from moisture and heat. |
What happens if I miss a dose?
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Take the missed dose as soon as you remember. However,
if it is almost time for the next dose, skip the missed
dose and take only the next regularly scheduled dose. Do
not take a double dose of this medication. |
What happens if I overdose?
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Seek emergency medical attention if an overdose is
suspected. |
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Symptoms of a hydrocodone and phenylephrine overdose may
include extreme drowsiness, dizziness, headache, seizures,
dry mouth, cold and clammy skin, flushing, nausea,
vomiting, difficult or decreased breathing, and
unconsciousness. |
What should I avoid while taking hydrocodone and
phenylephrine?
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Use caution when driving, operating machinery, or
performing other hazardous activities. Hydrocodone and
phenylephrine may cause dizziness or drowsiness. If you
experience dizziness or drowsiness, avoid these activities. |
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• |
Use alcohol cautiously. Alcohol may increase drowsiness
and dizziness while taking hydrocodone and phenylephrine. |
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• |
Hydrocodone and phenylephrine may increase the effects
of other drugs that cause drowsiness, including
antidepressants, alcohol, antihistamines, sedatives (used
to treat insomnia), pain relievers, anxiety medicines,
seizure medicines, and muscle relaxants. Tell your doctor
about all medicines that you are taking, and do not take
any other medicine without first talking to your doctor. |
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• |
Do not take other over-the-counter cough, cold, allergy,
diet, pain, or sleep medications while taking hydrocodone
and phenylephrine without first talking to your pharmacist
or doctor. Other medications may also contain hydrocodone,
phenylephrine, or other similar drugs, and you may
accidentally take too much of these medicines. |
What are the possible side effects of hydrocodone and
phenylephrine?
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If you experience any of the following serious side
effects, stop taking hydrocodone and phenylephrine and
seek emergency medical attention or contact your doctor
immediately: |
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a rare but serious allergic reaction (difficulty
breathing; closing of the throat; swelling of the lips,
tongue, or face; or hives); or |
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confusion, hallucinations, or unusual behavior. |
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Other, less serious side effects may be more likely to
occur. Continue to take hydrocodone and phenylephrine and
talk to your doctor if you experience |
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dizziness, drowsiness, or sleepiness; |
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restlessness or irritability; |
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nausea, vomiting, or decreased appetite; |
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• |
Hydrocodone is habit forming. It is possible become
physically and/ or psychologically dependent on the
medication. Do not take more than the prescribed amount of
medication or take it for longer than is directed by your
doctor. Withdrawal effects may occur if hydrocodone and
phenylephrine is stopped suddenly after several weeks of
continuous use. Your doctor may recommend a gradual
reduction in dose. |
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• |
Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems
unusual or that is especially bothersome. |
What other drugs will affect hydrocodone and
phenylephrine?
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• |
Do not take hydrocodone and phenylephrine if you have
taken a monoamine oxidase inhibitor (MAOI) such as
isocarboxazid (Marplan), phenelzine (Nardil),
tranylcypromine (Parnate), or selegiline (Eldepryl) in the
last 14 days. A dangerous drug interaction could occur,
leading to serious side effects. |
|
• |
Hydrocodone and phenylephrine may increase the effects
of other drugs that cause drowsiness, including
antidepressants, alcohol, sedatives (used to treat
insomnia), pain relievers, anxiety medicines, and muscle
relaxants. Tell your doctor about all medicines that you
are taking, and do not take any medicine unless your
doctor approves. |
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• |
Do not take other over-the-counter cough, cold, allergy,
diet, pain, or sleep medications while taking hydrocodone
and phenylephrine without first talking to your pharmacist
or doctor. Other medications may also contain hydrocodone,
phenylephrine, or other similar drugs, and you may
accidentally take too much of these medicines. |
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Drugs other than those listed here may also interact
with hydrocodone and phenylephrine. Talk to your doctor
and pharmacist before taking any prescription or
over-the-counter medicines, including vitamins, minerals,
and herbal products. |
Where can I get more information?
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Your pharmacist has more information about hydrocodone
and phenylephrine written for health professionals that
you may read. |
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Remember, keep this and all other medicines out of the
reach of children, never share your medicines with others,
and use this medication only for the indication prescribed |
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Every effort has been made to ensure that the
information provided by Cerner Multum, Inc. ('Multum') is
accurate, up-to-date, and complete, but no guarantee is
made to that effect. Drug information contained herein may
be time sensitive. Multum information has been compiled
for use by healthcare practitioners and consumers in the
United States and therefore Multum does not warrant that
uses outside of the United States are appropriate, unless
specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an
informational resource designed to assist licensed
healthcare practitioners in caring for their patients and/
or to serve consumers viewing this service as a supplement
to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The
absence of a warning for a given drug or drug combination
in no way should be construed to indicate that the drug or
drug combination is safe, effective or appropriate for any
given patient. Multum does not assume any responsibility
for any aspect of healthcare administered with the aid of
information Multum provides. The information contained
herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions,
allergic reactions, or adverse effects. If you have
questions about the drugs you are taking, check with your
doctor, nurse or pharmacist. |
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